Melanotan I (Afamelanotide) Product Brief
Ready-to-Sell Research Product Sheet
1. Compound Overview
Melanotan I, also known as Afamelanotide, is a synthetic analog of the naturally occurring alpha‑melanocyte‑stimulating hormone (α‑MSH).
It has been studied for its role in stimulating melanocortin receptors involved in skin pigmentation and photoprotection pathways.
Melanotan I has attracted research interest in dermatological studies related to pigmentation, UV response, and skin protective signaling mechanisms.
2. Mechanism of Interest
Melanotan I is studied for several biological mechanisms:
- Activation of melanocortin receptors (primarily MC1R)
• Stimulation of melanin production in melanocytes
• Potential enhancement of skin pigmentation pathways
• Possible photoprotective signaling against UV exposure
• Influence on melanocyte cellular activity
3. Research Areas Being Explored
- Skin pigmentation and melanogenesis research
• UV response and photoprotection studies
• Dermatological signaling pathways
• Melanocyte biology research
• Skin protective mechanisms
4. Suggested Research Vial Sizes
- 5 mg lyophilized vial
• 10 mg lyophilized vial
• 20 mg research vial
• 50 mg laboratory vial
5. Example Reconstitution Chart
Example mixing protocols commonly used in research contexts:
5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL concentration
10 mg vial + 2 mL bacteriostatic water = 5 mg/mL concentration
20 mg vial + 4 mL bacteriostatic water = 5 mg/mL concentration
These concentrations allow accurate measurement using insulin syringes for laboratory research settings.
6. Label Information for Vials
- Compound name: Melanotan I (Afamelanotide)
• Total amount per vial (mg)
• Lot / batch number
• Manufacturing date
• Storage instructions (2–8°C recommended)
• Research use only disclaimer
7. Market Positioning
Melanotan I is commonly positioned in the dermatology and pigmentation research peptide category.
It is frequently associated with research exploring:
- Melanin production pathways
• Skin pigmentation signaling
• Photoprotection models
• Dermatological peptide research
8. Example Research Stack Categories
- Melanotan I + Melanotan II
• Melanotan I + GHK-Cu
• Melanotan I + KPV
• Melanotan I + dermatological peptide stacks
9. Safety and Regulatory Notes
Melanotan I is not approved by the FDA for general cosmetic or medical use outside of specific clinical contexts and is commonly distributed as a research compound.
This document is intended for informational and research product description purposes only.

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