IGF-1 LR3 Product Brief

1. Compound Overview

IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is a modified analog of human insulin-like growth factor-1 designed for extended activity.
It contains an arginine substitution at position 3 and an additional 13-amino-acid extension, which reduces binding to IGF-binding proteins and prolongs its half-life.

IGF-1 LR3 is widely studied in research exploring cellular growth signaling, muscle tissue development, and regenerative biological pathways.

2. Mechanism of Interest

IGF-1 LR3 is studied for several biological mechanisms:

• Activation of the IGF-1 receptor (IGF-1R)
  • Stimulation of cellular growth and proliferation pathways
  • Increased protein synthesis signaling
  • Potential influence on muscle cell hypertrophy pathways
  • Interaction with growth hormone and endocrine signaling networks

3. Research Areas Being Explored

• Muscle growth and regeneration studies
  • Cellular proliferation and signaling pathways
  • Metabolic signaling research
  • Tissue repair and regeneration models
  • Growth hormone axis research

4. Safety and Regulatory Notes

IGF-1 LR3 is not approved by the FDA for medical treatment and is commonly distributed as a research compound.

This document is intended for informational and research product description purposes only.